Children’s Health

Minority and socioeconomically disadvantaged children have significantly higher rates of COVID-19 infection, a new study led by Children’s National Hospital researchers shows. These findings, reported online August 5 in Pediatrics, parallel similar health disparities for the novel coronavirus that have been found in adults, the authors state. COVID-19, an infection caused by the novel coronavirus
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Aug 5 2020 Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps (NETs) for severe cases of COVID-19. NETs are a fundamental arm of
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Cancer immunotherapy -; a treatment that better enables a patient’s own immune system to attack tumors -; has shown great potential against some cancers. Yet immunotherapy doesn’t work against all tumor types, and many patients who initially respond later develop resistance and relapse. Researchers at University of California San Diego School of Medicine and Moores
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An early blood test could detect which babies deprived of oxygen at birth are at risk of serious neurodisabilities like cerebral palsy and epilepsy. The prototype test looks for certain genes being switched on and off that are linked to long-term neurological issues. Further investigations of these genes may provide new targets for treating the
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Reviewed by Emily Henderson, B.Sc.Aug 4 2020 Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of–and a treatment for a previously unknown severe auto inflammatory syndrome affecting an 18-year-old girl since infancy. The technology, tailored to the patient’s own genetic code at a single cell
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A potentially safer, more effective chemotherapy treatment for patients with blood-related cancers, such as leukemia, who need a particular bone marrow transplant procedure is under study at the University of Arizona Health Sciences. The procedure is known as a haploidentical (half-matched) bone marrow transplantation, or “haplo-BMT,” providng an alternative source of stem cells for patients
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A mother’s own breast milk has infection-fighting factors and nutrients to help fuel growth and development in babies and may be easier to digest than formula. Providing this nourishment is particularly important for infants born prematurely, both while they are receiving care in a hospital’s neonatal intensive care unit (NICU) and after they are able
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A recent meningitis case at Children’s National Hospital raises serious concerns about antibiotic resistance in the common bacterium that caused it, researchers from the hospital write in a case report. Their findings, published online August 3 in the Journal of the Pediatric Infectious Disease Society, could change laboratory and clinical practice across the U.S. and
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